Serotonin and tryptophan metabolites, autoantibodies and gut microbiome in APECED

Serotonin and tryptophan metabolites, autoantibodies and gut microbiome in APECED

Objective: Intestinal autoimmunity with gastrointestinal (GI) dysfunction has been shown in patients with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). Patients lack entero-endocrine (EE) cells and have circulating autoantibodies (Aabs) against critical enzymes in serotoni...

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Bibliographic Details
Main Authors: Emmi Naskali, Katja Dettmer, Peter J Oefner, Pedro A B Pereira, Kai Krohn, Petri Auvinen, Annamari Ranki, Nicolas Kluger
Format: Article
Language:English
Published: Bioscientifica 2019-01-01
Series:Endocrine Connections
Subjects:
APECED
serotonin
diarrhea
constipation
entero-endrocrine cells
Paneth cells
Online Access:https://ec.bioscientifica.com/view/journals/ec/8/1/EC-18-0513.xml

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https://ec.bioscientifica.com/view/journals/ec/8/1/EC-18-0513.xml

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