Astragaloside IV Protects 6-Hydroxydopamine-Induced SH-SY5Y Cell Model of Parkinson’s Disease via Activating the JAK2/STAT3 Pathway

Astragaloside IV Protects 6-Hydroxydopamine-Induced SH-SY5Y Cell Model of Parkinson’s Disease via Activating the JAK2/STAT3 Pathway

ObjectivesAstragaloside IV (AS-IV), the main active component of Astragalus membranaceus, bears anti-inflammatory, antioxidant, and neuroprotective activity. Parkinson’s disease (PD) is a common neurodegenerative disease. This study explored the protective effect of AS-IV on the cell model of PD.Mat...

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Bibliographic Details
Main Authors: ZhengHu Xu, Dongfeng Yang, Xiaojing Huang, Huai Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Neuroscience
Subjects:
Parkinson’s disease
astragaloside IV
JAK2/STAT3 pathway
SH-SY5Y cells
inflammation
oxidative stress
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.631501/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2021.631501/full

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