Parallel roles of transcription factors dFOXO and FER2 in the development and maintenance of dopaminergic neurons.
Forkhead box (FOXO) proteins are evolutionarily conserved, stress-responsive transcription factors (TFs) that can promote or counteract cell death. Mutations in FOXO genes are implicated in numerous pathologies, including age-dependent neurodegenerative disorders, such as Parkinson's disease (P...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-03-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC5864087?pdf=render |