Protective Effects of Fucoidan on Epithelial-Mesenchymal Transition of Retinal Pigment Epithelial Cells and Progression of Proliferative Vitreoretinopathy

Protective Effects of Fucoidan on Epithelial-Mesenchymal Transition of Retinal Pigment Epithelial Cells and Progression of Proliferative Vitreoretinopathy

Background/Aims: Proliferative vitreoretinopathy (PVR) is a severe blinding complication of rhegmatogenous retinal detachment. Epithelial-mesenchymal transition (EMT) of retinal pigment epithelial (RPE) cells is thought to play a pivotal role in the pathogenesis of PVR. Fucoidan, a marine extract, r...

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Bibliographic Details
Main Authors: Yao Zhang, Dongwan Zhao, Shuai Yang, Haipei Yao, Min Li, Chun Zhao, Jingfa Zhang, Guo-Tong Xu, Hui Li, Fang Wang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-04-01
Series:Cellular Physiology and Biochemistry
Subjects:
Fucoidan
Epithelial-mesenchymal transition
Retinal pigment epithelium
Proliferative vitreoretinopathy
Online Access:https://www.karger.com/Article/FullText/489246

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https://www.karger.com/Article/FullText/489246

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