Cx43 and AKAP95 regulate G1/S conversion by competitively binding to cyclin E1/E2 in lung cancer cells

Cx43 and AKAP95 regulate G1/S conversion by competitively binding to cyclin E1/E2 in lung cancer cells

Abstract Background This study aimed to overexpress or silence connexin 43 (Cx43) and A‐kinase anchoring protein 95 (AKAP95) in human A549 cells to explore their effects on cyclins and on G1/S conversion when the interrelationship of Cx43, AKAP95, and cyclin E1/E2 changes. Methods The study mainly u...

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Bibliographic Details
Main Authors: Renzhen Chen, Yu Chen, Yangyang Yuan, Xuan Zou, Qian Sun, Hongyan Lin, Xiaoyi Chen, Mingda Liu, Zifeng Deng, Youliang Yao, Dongbei Guo, Yongxing Zhang
Format: Article
Language:English
Published: Wiley 2020-06-01
Series:Thoracic Cancer
Subjects:
A‐kinase anchoring protein 95 (AKAP95)
competitively binding
connexin 43 (Cx43)
cyclin E1/E2
Online Access:https://doi.org/10.1111/1759-7714.13435

Internet

https://doi.org/10.1111/1759-7714.13435

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