Spatial separation of two different pathways accounting for the generation of calcium signals in astrocytes.

Astrocytes integrate and process synaptic information and exhibit calcium (Ca2+) signals in response to incoming information from neighboring synapses. The generation of Ca2+ signals is mostly attributed to Ca2+ release from internal Ca2+ stores evoked by an elevated metabotropic glutamate receptor...

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Bibliographic Details
Main Authors: Franziska Oschmann, Konstantin Mergenthaler, Evelyn Jungnickel, Klaus Obermayer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-02-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5330534?pdf=render