Butyrophilin-like 2 regulates site-specific adaptations of intestinal γδ intraepithelial lymphocytes

Butyrophilin-like 2 regulates site-specific adaptations of intestinal γδ intraepithelial lymphocytes

Panea et al showed that epithelia-specific butyrophilinlike 2 (Btnl2) suppressed homeostatic proliferation of γδ intraepithelial lymphocytes (IELs) preferentially in the ileum and used high throughput transcriptomic characterization of Btnl2-deficient γδ IELs to demonstrate that Btnl2 impacts γδ TCR...

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Bibliographic Details
Main Authors: Casandra Panea, Ruoyu Zhang, Jeffrey VanValkenburgh, Min Ni, Christina Adler, Yi Wei, Francisca Ochoa, Jennifer Schmahl, Yajun Tang, Chia-Jen Siao, William Poueymirou, Jennifer Espert, Wei Keat Lim, Gurinder S. Atwal, Andrew J. Murphy, Matthew A. Sleeman, Zaruhi Hovhannisyan, Sokol Haxhinasto
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02438-x

Internet

https://doi.org/10.1038/s42003-021-02438-x

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