Methotrexate induces DNA damage and inhibits homologous recombination repair in choriocarcinoma cells

Methotrexate induces DNA damage and inhibits homologous recombination repair in choriocarcinoma cells

Lisha Xie,1,* Tiancen Zhao,1,2,* Jing Cai,1 You Su,1 Zehua Wang,1 Weihong Dong1 1Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 2Department of Obstetrics and Gynecology, Central Hospital of Wuhan, Wuhan, China *These...

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Bibliographic Details
Main Authors: Xie L, Zhao T, Cai J, Su Y, Wang Z, Dong W
Format: Article
Language:English
Published: Dove Medical Press 2016-11-01
Series:OncoTargets and Therapy
Subjects:
Choriocarcinoma
Chemotherapy hypersensitivity
DNA double-strand break
RAD51
p53
Online Access:https://www.dovepress.com/methotrexate-induces-dna-damage-and-inhibits-homologous-recombination--peer-reviewed-article-OTT

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https://www.dovepress.com/methotrexate-induces-dna-damage-and-inhibits-homologous-recombination--peer-reviewed-article-OTT

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