Interactogeneous: disease gene prioritization using heterogeneous networks and full topology scores.

Disease gene prioritization aims to suggest potential implications of genes in disease susceptibility. Often accomplished in a guilt-by-association scheme, promising candidates are sorted according to their relatedness to known disease genes. Network-based methods have been successfully exploiting t...

Full description

Bibliographic Details
Main Authors: Joana P Gonçalves, Alexandre P Francisco, Yves Moreau, Sara C Madeira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3501465?pdf=render