Falstatin, a cysteine protease inhibitor of Plasmodium falciparum, facilitates erythrocyte invasion.
Erythrocytic malaria parasites utilize proteases for a number of cellular processes, including hydrolysis of hemoglobin, rupture of erythrocytes by mature schizonts, and subsequent invasion of erythrocytes by free merozoites. However, mechanisms used by malaria parasites to control protease activity...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2006-11-01
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| Series: | PLoS Pathogens |
| Online Access: | http://europepmc.org/articles/PMC1630708?pdf=render |