Development of <sup>18</sup>F-Labeled Radiotracers for PET Imaging of the Adenosine A<sub>2A</sub> Receptor: Synthesis, Radiolabeling and Preliminary Biological Evaluation

Development of <sup>18</sup>F-Labeled Radiotracers for PET Imaging of the Adenosine A<sub>2A</sub> Receptor: Synthesis, Radiolabeling and Preliminary Biological Evaluation

The adenosine A<sub>2A</sub> receptor (A<sub>2A</sub>R) represents a potential therapeutic target for neurodegenerative diseases. Aiming at the development of a positron emission tomography (PET) radiotracer to monitor changes of receptor density and/or occupancy during the A...

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Bibliographic Details
Main Authors: Thu Hang Lai, Susann Schröder, Magali Toussaint, Sladjana Dukić-Stefanović, Mathias Kranz, Friedrich-Alexander Ludwig, Steffen Fischer, Jörg Steinbach, Winnie Deuther-Conrad, Peter Brust, Rareş-Petru Moldovan
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
adenosine receptors
A2A receptor
fluorine-18
positron emission tomography
vipadenant
Online Access:https://www.mdpi.com/1422-0067/22/5/2285

Internet

https://www.mdpi.com/1422-0067/22/5/2285

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