Correlation between initial tumour volume and treatment duration on Dabrafenib: observation study of subjects with BRAF mutant melanoma on the BRF112680 trial

Correlation between initial tumour volume and treatment duration on Dabrafenib: observation study of subjects with BRAF mutant melanoma on the BRF112680 trial

Abstract Background Planar-based measurements of lesions in metastatic melanoma have limitations in estimating tumor burden of a patient and in predicting response to treatment. Volumetric imaging might add predictive value to Response criteria in Solid Tumor (RECIST)-measurement. Based on clinical...

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Bibliographic Details
Main Authors: Arwa Ali, Monica Dumbrava, Kylie Riddell, Nina Stewart, Robyn Ward, Ahmed K. Ibrahim, Melvin Chin
Format: Article
Language:English
Published: BMC 2020-04-01
Series:BMC Cancer
Subjects:
Tumor volume
RECIST-base assessment
Predictive biomarkers
BRAF-inhibitors
Treatment duration
Metastatic melanoma
Online Access:http://link.springer.com/article/10.1186/s12885-020-06848-8

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http://link.springer.com/article/10.1186/s12885-020-06848-8

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