Antitumoral effects of Amblyomma sculptum Berlese saliva in neuroblastoma cell lines involve cytoskeletal deconstruction and cell cycle arrest

Antitumoral effects of Amblyomma sculptum Berlese saliva in neuroblastoma cell lines involve cytoskeletal deconstruction and cell cycle arrest

Abstract The antitumor properties of ticks salivary gland extracts or recombinant proteins have been reported recently, but little is known about the antitumor properties of the secreted components of saliva. The goal of this study was to investigate the in vitro effect of the saliva of the hard ti...

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Main Authors: Thatyanne Gradowski do Nascimento, Priscilla Santos Vieira, Sheron Campos Cogo, Marcela Ferreira Dias-Netipanyj, Nilton de França Junior, Diana Aparecida Dias Câmara, Allan Saj Porcacchia, Ronaldo Zucatelli Mendonça, Andréa Novais Moreno-Amaral, Paulo Luiz de Sá Junior, Simone Michaela Simons, Luciana Zischler, Selene Elifio-Esposito
Format: Article
Language:English
Published: Colégio Brasileiro de Parasitologia Veterinaria 2019-02-01
Series:Revista Brasileira de Parasitologia Veterinária
Subjects:
Tick saliva
animal toxin
tumor cell death
pediatric cancer
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-29612019000100126&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-29612019000100126&lng=en&tlng=en

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