Recombinant production of human interleukin 6 in Escherichia coli.

In this study, we compared basic expression approaches for the efficient expression of bioactive recombinant human interleukin-6 (IL6), as an example for a difficult-to-express protein. We tested these approaches in a laboratory scale in order to pioneer the commercial production of this protein in...

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Bibliographic Details
Main Authors: Henrik Nausch, Jana Huckauf, Roswitha Koslowski, Udo Meyer, Inge Broer, Heike Mikschofsky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3553018?pdf=render