Preserving cortico-striatal function: Deep brain stimulation in Huntington's disease

Huntington’s disease (HD) is an incurable neurodegenerative disease characterized by the triad of chorea, cognitive dysfunction and psychiatric disturbances. Since the discovery of the HD gene, the pathogenesis has been outlined, but to date a cure has not been found. Disease modifying therapies ar...

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Bibliographic Details
Main Authors: Sean J Nagel, Andre G Machado, John Thomas Gale, Darlene Angela Lobel, Mayur ePandya
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Systems Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnsys.2015.00032/full