Blood group substances as potential therapeutic agents for the prevention and treatment of infection with noroviruses proving novel binding patterns in human tissues.

Blood group substances as potential therapeutic agents for the prevention and treatment of infection with noroviruses proving novel binding patterns in human tissues.

Blood group-related glycans determining ABO and Lewis blood groups are known to function as attachment factors for most of the norovirus (NoV) strains. To identify binding specificity of each NoV, recombinant norovirus-like particles (VLPs) and human saliva samples with different ABO, Lewis phenotyp...

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Bibliographic Details
Main Authors: Shin Yazawa, Takehiko Yokobori, Gen Ueta, Munenori Ide, Bolag Altan, Aksara Thongprachum, Toyo Nishimura, Tamiko Nakajima, Yoshihiko Kominato, Takayuki Asao, Abby R Saniabadi, Kiyoshi Furukawa, Hiroyuki Kuwano, Jacques Le Pendu, Hiroshi Ushijima
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3928367?pdf=render

Internet

http://europepmc.org/articles/PMC3928367?pdf=render

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