Interleukin 7 plays a role in T lymphocyte apoptosis inhibition driven by mesenchymal stem cell without favoring proliferation and cytokines secretion.

Since 2004, when a case report describing the use of human mesenchymal stem cells (hMSCs) infusion as a therapy for GVHD after bone marrow transplantation, a new perspective in MSC function emerged. Since then hMSCs immunomodulatory potential became the target of several studies. Although great prog...

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Bibliographic Details
Main Authors: Marilia Normanton, Heliene Alvarenga, Nelson Hamerschlak, Andreza Ribeiro, Andrea Kondo, Luiz Vicente Rizzo, Luciana Cavalheiro Marti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4153662?pdf=render