APC germline hepatoblastomas demonstrate cisplatin-induced intratumor tertiary lymphoid structures

APC germline hepatoblastomas demonstrate cisplatin-induced intratumor tertiary lymphoid structures

Hepatoblastoma (HB) is the most common liver cancer in children. We aimed to characterize HB related to APC (Adenomatous Polyposis Coli) germline mutation (APC-HB). This French multicentric retrospective study included 12 APC-HB patients under 5 at diagnosis. Clinical features of APC-HB were compare...

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Bibliographic Details
Main Authors: Guillaume Morcrette, Theo Z Hirsch, Elise Badour, Jill Pilet, Stefano Caruso, Julien Calderaro, Yoann Martin, Sandrine Imbeaud, Eric Letouzé, Sandra Rebouissou, Sophie Branchereau, Sophie Taque, Christophe Chardot, Catherine Guettier, Jean-Yves Scoazec, Monique Fabre, Laurence Brugières, Jessica Zucman-Rossi
Format: Article
Language:English
Published: Taylor & Francis Group 2019-06-01
Series:OncoImmunology
Subjects:
pediatric neoplasm
adenomatous polyposis coli
antitumor immunity
liver tumor
immunogenic cell death
Online Access:http://dx.doi.org/10.1080/2162402X.2019.1583547

Internet

http://dx.doi.org/10.1080/2162402X.2019.1583547

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