Prophylactic Zinc and Therapeutic Selenium Administration Increases the Antioxidant Enzyme Activity in the Rat Temporoparietal Cortex and Improves Memory after a Transient Hypoxia-Ischemia

Prophylactic Zinc and Therapeutic Selenium Administration Increases the Antioxidant Enzyme Activity in the Rat Temporoparietal Cortex and Improves Memory after a Transient Hypoxia-Ischemia

In the cerebral hypoxia-ischemia rat model, the prophylactic administration of zinc can cause either cytotoxicity or preconditioning effect, whereas the therapeutic administration of selenium decreases the ischemic damage. Herein, we aimed to explore whether supplementation of low doses of prophylac...

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Bibliographic Details
Main Authors: Constantino Tomas-Sanchez, Victor-Manuel Blanco-Alvarez, Daniel Martinez-Fong, Juan-Antonio Gonzalez-Barrios, Alejandro Gonzalez-Vazquez, Ana-Karina Aguilar-Peralta, Maricela Torres-Soto, Guadalupe Soto-Rodriguez, Ilhuicamina Daniel Limón, Eduardo Brambila, Lourdes Millán-Pérez-Peña, Jorge Cebada, Carlos E. Orozco-Barrios, Bertha Alicia Leon-Chavez
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2018/9416432

Internet

http://dx.doi.org/10.1155/2018/9416432

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