Focus on Chirality of HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors

Chiral HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) are of great interest since one enantiomer is often more potent than the corresponding counterpart against the HIV-1 wild type (WT) and the HIV-1 drug resistant mutant strains. This review exemplifies the various studies made to i...

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Bibliographic Details
Main Authors: Valeria Famiglini, Romano Silvestri
Format: Article
Language:English
Published: MDPI AG 2016-02-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/21/2/221