First-Breath-Induced Type 2 Pathways Shape the Lung Immune Environment

First-Breath-Induced Type 2 Pathways Shape the Lung Immune Environment

From birth onward, the lungs are exposed to the external environment and therefore harbor a complex immunological milieu to protect this organ from damage and infection. We investigated the homeostatic role of the epithelium-derived alarmin interleukin-33 (IL-33) in newborn mice and discovered the i...

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Bibliographic Details
Main Authors: Simona Saluzzo, Anna-Dorothea Gorki, Batika M.J. Rana, Rui Martins, Seth Scanlon, Philipp Starkl, Karin Lakovits, Anastasiya Hladik, Ana Korosec, Omar Sharif, Joanna M. Warszawska, Helen Jolin, Ildiko Mesteri, Andrew N.J. McKenzie, Sylvia Knapp
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:Cell Reports
Subjects:
newborn
lung
immune homeostasis
alarmin
first breath
alveolar macrophage
pneumoniae
S. pneumoniae
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717301419

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http://www.sciencedirect.com/science/article/pii/S2211124717301419

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