Serum Metabolites Differentiate Amnestic Mild Cognitive Impairment From Healthy Controls and Predict Early Alzheimer's Disease via Untargeted Lipidomics Analysis

Serum Metabolites Differentiate Amnestic Mild Cognitive Impairment From Healthy Controls and Predict Early Alzheimer's Disease via Untargeted Lipidomics Analysis

Background and Aim: Alzheimer's disease (AD) is the most common type of dementia and presents with metabolic perturbations early in the disease process. In order to explore biomarkers useful in predicting early AD, we compared serum metabolites among patients suffering different stages of AD.Me...

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Bibliographic Details
Main Authors: Lumi Zhang, Lingxiao Li, Fanxia Meng, Jie Yu, Fangping He, Yajie Lin, Yujie Su, Mengjie Hu, Xiaoyan Liu, Yang Liu, Benyan Luo, Guoping Peng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Neurology
Subjects:
Alzheimer's disease
amnestic mild cognitive impairment
untargeted lipidomics
serum
cholesteryl ester
ganglioside GM3
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2021.704582/full

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https://www.frontiersin.org/articles/10.3389/fneur.2021.704582/full

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