CTL Attenuation Regulated by PS1 in Cancer-Associated Fibroblast

CTL Attenuation Regulated by PS1 in Cancer-Associated Fibroblast

Objective: Cancer-associated fibroblasts (CAFs) were associated with tumor progression in the tumor microenvironment (TME). However, their immunosuppressive roles in protecting cancer cells from the attack by cytotoxic T lymphocytes (CTLs) are not fully clear. In this study, we investigated whether...

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Bibliographic Details
Main Authors: Hongyu Zhang, Rong Jiang, Jinhua Zhou, Juan Wang, Yuejuan Xu, He Zhang, Yanzheng Gu, Fengqing Fu, Yu Shen, Guangbo Zhang, Lanlan Feng, Xueguang Zhang, Youguo Chen, Fangrong Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Immunology
Subjects:
tumor microenvironment
cancer-associated fibroblasts
immunosuppression
PS1
IL-1β
WNT/β-catenin pathway
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00999/full

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https://www.frontiersin.org/article/10.3389/fimmu.2020.00999/full

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