Effect of the Natural Product Triptolide on Pancreatic Cancer: A Systematic Review of Preclinical Studies

Objective: Triptolide (TL), a natural product isolated from Tripterygium wilfordii Hook F (TwHF), shows potent anticancer effects in vitro and in vivo. We aimed to summary the biochemical mechanisms through which TL has been shown to induce apoptosis, autophagy and inhibit angiogenesis in pancreatic...

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Bibliographic Details
Main Authors: Chi Zhang, Xiao-Juan He, Li Li, Cheng Lu, Ai-Ping Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00490/full