Upregulation of microRNA-93-5p/microRNA-4668-5p, and promoter methylation of matrix metalloproteinase-3 and interleukin-16 genes in Turkish patients with rheumatoid arthritis

Upregulation of microRNA-93-5p/microRNA-4668-5p, and promoter methylation of matrix metalloproteinase-3 and interleukin-16 genes in Turkish patients with rheumatoid arthritis

Aim of the work: To investigate promoter methylation of matrix metalloproteinase-3 (MMP-3) and interleukin-16 (IL-16) genes with the expression of miRNA-93-5p and miRNA-4668-5p which target these genes in rheumatoid arthritis (RA), respectively. Patients and methods: The study included 49 RA patient...

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Bibliographic Details
Main Authors: Zulfinaz Betul Celik, Sengul Tural, Ahmet Kivanc Cengiz, Nurten Kara, Gamze Alayli
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Egyptian Rheumatologist
Subjects:
Rheumatoid arthritis
MMP-3
IL-16
Methylation
MicroRNA
Online Access:http://www.sciencedirect.com/science/article/pii/S1110116420300594

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http://www.sciencedirect.com/science/article/pii/S1110116420300594

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