GnRH Antagonists Produce Differential Modulation of the Signaling Pathways Mediated by GnRH Receptors

GnRH Antagonists Produce Differential Modulation of the Signaling Pathways Mediated by GnRH Receptors

Commercial gonadotropin-releasing hormone (GnRH) antagonists differ by 1−2 amino acids and are used to inhibit gonadotropin production during assisted reproduction technologies (ART). In this study, potencies of three GnRH antagonists, Cetrorelix, Ganirelix and Teverelix, in inhibiting GnR...

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Bibliographic Details
Main Authors: Samantha Sperduti, Silvia Limoncella, Clara Lazzaretti, Elia Paradiso, Laura Riccetti, Sara Turchi, Ilaria Ferrigno, Jessika Bertacchini, Carla Palumbo, Francesco Potì, Salvatore Longobardi, Robert P. Millar, Manuela Simoni, Claire L. Newton, Livio Casarini
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:International Journal of Molecular Sciences
Subjects:
gonadotropin-releasing hormone (gnrh)
antagonist
pituitary
luteinizing hormone (lh)
follicle-stimulating hormone (fsh)
gonadotropins
assisted reproduction techniques (art)
cetrorelix
ganirelix
teverelix
Online Access:https://www.mdpi.com/1422-0067/20/22/5548

Internet

https://www.mdpi.com/1422-0067/20/22/5548

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