HMGB1 promotes a p38MAPK associated non-infectious inflammatory response pathway in human fetal membranes.

OBJECTIVE: Spontaneous preterm birth (PTB) and preterm prelabor rupture of membranes (pPROM) are major pregnancy complications often associated with a fetal inflammatory response. Biomolecular markers of this fetal inflammatory response to both infectious and non-infectious risk factors and their co...

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Bibliographic Details
Main Authors: Sarah Bredeson, John Papaconstantinou, James H Deford, Talar Kechichian, Tariq A Syed, George R Saade, Ramkumar Menon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4254744?pdf=render