Identification of kinases regulating prostate cancer cell growth using an RNAi phenotypic screen.

Identification of kinases regulating prostate cancer cell growth using an RNAi phenotypic screen.

As prostate cancer progresses to castration-resistant disease, there is an increase in signal transduction activity. Most castration-resistant prostate tumors continue to express the androgen receptor (AR) as well as androgen-responsive genes, despite the near absence of circulating androgen in thes...

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Bibliographic Details
Main Authors: Hilary Whitworth, Shriti Bhadel, Melissa Ivey, Mark Conaway, Andrea Spencer, Ronald Hernan, Heather Holemon, Daniel Gioeli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3384611?pdf=render

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http://europepmc.org/articles/PMC3384611?pdf=render

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