Microglia Implicated in Tauopathy in the Striatum of Neurodegenerative Disease Patients from Genotype to Phenotype

We found interactions between dopamine and oxidative damage in the striatum involved in advanced neurodegeneration, which probably change the microglial phenotype. We observed possible microglia dystrophy in the striatum of neurodegenerative brains. To investigate the interactions between oxidative...

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Bibliographic Details
Main Authors: Huifangjie Li, William C. Knight, Pengfei Yang, Yingqiu Guo, Joel S. Perlmutter, John C. Morris, Randall J. Bateman, Tammie L. S. Benzinger, Jinbin Xu
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/17/6047