Large-Scale Hematopoietic Differentiation of Human Induced Pluripotent Stem Cells Provides Granulocytes or Macrophages for Cell Replacement Therapies

Interleukin-3 (IL-3) is capable of supporting the proliferation of a broad range of hematopoietic cell types, whereas granulocyte colony-stimulating factor (G-CSF) and macrophage CSF (M-CSF) represent critical cytokines in myeloid differentiation. When this was investigated in a pluripotent-stem-cel...

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Bibliographic Details
Main Authors: Nico Lachmann, Mania Ackermann, Eileen Frenzel, Steffi Liebhaber, Sebastian Brennig, Christine Happle, Dirk Hoffmann, Olga Klimenkova, Doreen Lüttge, Theresa Buchegger, Mark Philipp Kühnel, Axel Schambach, Sabina Janciauskiene, Constanca Figueiredo, Gesine Hansen, Julia Skokowa, Thomas Moritz
Format: Article
Language:English
Published: Elsevier 2015-02-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671115000260