Large-Scale Hematopoietic Differentiation of Human Induced Pluripotent Stem Cells Provides Granulocytes or Macrophages for Cell Replacement Therapies
Interleukin-3 (IL-3) is capable of supporting the proliferation of a broad range of hematopoietic cell types, whereas granulocyte colony-stimulating factor (G-CSF) and macrophage CSF (M-CSF) represent critical cytokines in myeloid differentiation. When this was investigated in a pluripotent-stem-cel...
Main Authors: | Nico Lachmann, Mania Ackermann, Eileen Frenzel, Steffi Liebhaber, Sebastian Brennig, Christine Happle, Dirk Hoffmann, Olga Klimenkova, Doreen Lüttge, Theresa Buchegger, Mark Philipp Kühnel, Axel Schambach, Sabina Janciauskiene, Constanca Figueiredo, Gesine Hansen, Julia Skokowa, Thomas Moritz |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-02-01
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Series: | Stem Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213671115000260 |
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