Vitamin D Promotes Trophoblast Cell Induced Separation of Vascular Smooth Muscle Cells in Vascular Remodeling via Induction of G-CSF

Vitamin D Promotes Trophoblast Cell Induced Separation of Vascular Smooth Muscle Cells in Vascular Remodeling via Induction of G-CSF

Vitamin D deficiency is associated with complications of pregnancy such as pre-eclampsia, fetal growth restriction, and miscarriage, all of which are also associated with incomplete spiral artery (SpA) remodeling. We have previously shown that both uterine natural killer (uNK) cells and extravillous...

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Bibliographic Details
Main Authors: Joy Yue Zhang, Peihuang Wu, Danyang Chen, Fen Ning, Qinsheng Lu, Xiu Qiu, Martin Hewison, Jennifer A. Tamblyn, Mark D. Kilby, Gendie E. Lash
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
vitamin D
spiral artery remodeling
extravillous trophoblast cells
G-CSF
VSMC phenotypic switching
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.601043/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2020.601043/full

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