Human CD8+CD28− T suppressor cells expanded by common gamma chain (γc) cytokines retain steady allospecific suppressive capacity in vivo

Human CD8+CD28− T suppressor cells expanded by common gamma chain (γc) cytokines retain steady allospecific suppressive capacity in vivo

Abstract Background CD8+CD28− T suppressor (Ts) cells play critical role in transplant tolerance. Our previous study has generated CD8+CD28− Ts cells in vitro which exert robust allospecific suppressive capacity in vitro. Results CD8+CD28− Ts cells were expanded by stimulating human CD8+ T cells wit...

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Bibliographic Details
Main Authors: Guihuan Liu, Yuming Yu, Fu Feng, Ping Zhu, Hua Zhang, Danni Zhang, Xiaoqiang Feng, Zedan Zhang, Yanjun Liu
Format: Article
Language:English
Published: BMC 2020-04-01
Series:BMC Immunology
Subjects:
CD8+CD28− T suppressor cells
Common gamma chain cytokines
Transplant tolerance
Alloantigen specific tolerance
Online Access:http://link.springer.com/article/10.1186/s12865-020-00354-z

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http://link.springer.com/article/10.1186/s12865-020-00354-z

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