Gemcitabine and arabinosylcytosin pharmacogenomics: genome-wide association and drug response biomarkers.

Cancer patients show large individual variation in their response to chemotherapeutic agents. Gemcitabine (dFdC) and AraC, two cytidine analogues, have shown significant activity against a variety of tumors. We previously used expression data from a lymphoblastoid cell line-based model system to ide...

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Bibliographic Details
Main Authors: Liang Li, Brooke L Fridley, Krishna Kalari, Gregory Jenkins, Anthony Batzler, Richard M Weinshilboum, Liewei Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2770319?pdf=render