Blood-Based Biomarkers Predictive of Metformin Target Engagement in Fragile X Syndrome

Recent advances in neurobiology have provided several molecular entrees for targeted treatments for Fragile X syndrome (FXS). However, the efficacy of these treatments has been demonstrated mainly in animal models and has not been consistently predictive of targeted drugs’ response in the prepondera...

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Bibliographic Details
Main Authors: Mittal Jasoliya, Heather Bowling, Ignacio Cortina Petrasic, Blythe Durbin-Johnson, Eric Klann, Aditi Bhattacharya, Randi Hagerman, Flora Tassone
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Brain Sciences
Subjects:
RAS
Online Access:https://www.mdpi.com/2076-3425/10/6/361