Short or Long Antibiotic Regimes in Orthopaedics (SOLARIO): a randomised controlled open-label non-inferiority trial of duration of systemic antibiotics in adults with orthopaedic infection treated operatively with local antibiotic therapy

Abstract Background Orthopaedic infections, such as osteomyelitis, diabetic foot infection and prosthetic joint infection, are most commonly treated by a combination of surgical debridement and a prolonged course of systemic antibiotics, usually for at least 4–6 weeks. Use of local antibiotics, impl...

Full description

Bibliographic Details
Main Authors: Maria Dudareva, Michelle Kümin, Werner Vach, Klaus Kaier, Jamie Ferguson, Martin McNally, Matthew Scarborough
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Trials
Subjects:
Online Access:https://doi.org/10.1186/s13063-019-3832-3