In Vivo Evaluation of Blood Based and Reference Tissue Based PET Quantifications of [11C]DASB in the Canine Brain.

This first-in-dog study evaluates the use of the PET-radioligand [11C]DASB to image the density and availability of the serotonin transporter (SERT) in the canine brain. Imaging the serotonergic system could improve diagnosis and therapy of multiple canine behavioural disorders. Furthermore, as many...

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Bibliographic Details
Main Authors: Nick Van Laeken, Olivia Taylor, Ingeborgh Polis, Sara Neyt, Ken Kersemans, Andre Dobbeleir, Jimmy Saunders, Ingeborg Goethals, Kathelijne Peremans, Filip De Vos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4747581?pdf=render