DDX23, an Evolutionary Conserved dsRNA Sensor, Participates in Innate Antiviral Responses by Pairing With TRIF or MAVS

DDX23, an Evolutionary Conserved dsRNA Sensor, Participates in Innate Antiviral Responses by Pairing With TRIF or MAVS

DExD/H-box helicases play essential roles in RNA metabolism, and emerging data suggests that they have additional functions in antiviral immunity across species. However, little is known about this evolutionarily conserved family in antiviral responses in lower species. Here, through isolation of po...

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Bibliographic Details
Main Authors: Jie Ruan, Yange Cao, Tao Ling, Peiyi Li, Shengpeng Wu, Dezhi Peng, Yao Wang, Xin Jia, Shangwu Chen, Anlong Xu, Shaochun Yuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Immunology
Subjects:
amphioxus (lancelet)
innate antiviral immunity
dsRNA sensors
RNA Helicases
DDX23
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02202/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02202/full

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