Acute glufosinate-based herbicide treatment in rats leads to increased ocular interleukin-1β and c-Fos protein levels, as well as intraocular pressure

Glufosinate is a common herbicide with neurotoxic effects, leading to seizures, convulsions and memory loss. Glufosinate indirectly induces glutamate toxicity by inhibiting glutamine synthesis in astrocytes. Here, we studied the acute toxic effects of a glufosinate-based herbicide in rat optic nerve...

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Bibliographic Details
Main Authors: Selim Çomaklı, Çiğdem Sevim, George Kontadakis, Elif Doğan, Ali Taghizadehghalehjoughi, Mustafa Özkaraca, Michael Aschner, Taxiarchis Konstantinos Nikolouzakis, Aristides Tsatsakis
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Toxicology Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750018307819