Measles skin rash: Infection of lymphoid and myeloid cells in the dermis precedes viral dissemination to the epidermis.

Measles is characterized by fever and a maculopapular skin rash, which is accompanied by immune clearance of measles virus (MV)-infected cells. Histopathological analyses of skin biopsies from humans and non-human primates (NHPs) with measles rash have identified MV-infected keratinocytes and mononu...

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Main Authors: Brigitta M Laksono, Paola Fortugno, Bernadien M Nijmeijer, Rory D de Vries, Sonia Cordisco, Thijs Kuiken, Teunis B H Geijtenbeek, W Paul Duprex, Francesco Brancati, Rik L de Swart
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-10-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008253