A rapid and simple RP-HPLC method for quantification of desipramine in human plasma

A high-performance liquid chromatographic (HPLC) method for the determination of antidepressant drug desipramine as active metabolite of imipramine in plasma is reported. The method is based on the purple chromogen formed by displacement reaction of desipramine with 7,7,8,8-tetracyanoquinodimethane...

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Bibliographic Details
Main Authors: Önal Armağan, Öztunç Aysel
Format: Article
Language:English
Published: De Gruyter 2011-11-01
Series:Reviews in Analytical Chemistry
Subjects:
Online Access:https://doi.org/10.1515/REVAC.2011.102