Clinical evaluation of a non-purified direct molecular assay for the detection of Clostridioides difficile toxin genes in stool specimens.

Recently, a new rapid assay for the detection of tcdB gene of Clostridioides difficile was developed using the GENECUBE. The assay can directly detect the tcdB gene from stool samples without a purification in approximately 35 minutes with a few minutes of preparation process. We performed a prospec...

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Bibliographic Details
Main Authors: Toshinori Hara, Hiromichi Suzuki, Tadatomo Oyanagi, Norito Koyanagi, Akihito Ushiki, Naoki Kawabata, Miki Goto, Yukio Hida, Yuji Yaguchi, Kiyoko Tamai, Shigeyuki Notake, Yosuke Kawashima, Akio Sugiyama, Keiichi Uemura, Seiya Kashiyama, Toru Nanmoku, Satoshi Suzuki, Hiroshi Yamazaki, Hideki Kimura, Hiroyuki Kunishima, Hiroki Ohge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0234119