Conditional deletion of HDAC4 from collagen type 2α1-expressing cells increases angiogenesis in vivo

Conditional deletion of HDAC4 from collagen type 2α1-expressing cells increases angiogenesis in vivo

Abstract Background HDAC4 is a key regulator of chondrocyte hypertrophy and skeletal development, but it is not clear whether the increase in vascular invasion at growth plates is related to HDAC4 expression. To determine it, we investigated the relationship between HDAC4 and angiogenesis in both in...

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Bibliographic Details
Main Authors: Lilan Gao, Shengchun Li, Xiaochun Wei, Guoqing Du, Dennis Wei, Lei Wei
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Molecular Medicine
Subjects:
Histone deacetylase 4
Growth plate
Mice
Chondrocytes
Angiogenesis
Online Access:http://link.springer.com/article/10.1186/s10020-020-00154-6

Internet

http://link.springer.com/article/10.1186/s10020-020-00154-6

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