Immunization with Dendritic Cells Pulsed ex vivo with Recombinant Chlamydial Protease-Like Activity Factor Induces Protective Immunity Against Genital Chlamydia muridarum Challenge

Immunization with Dendritic Cells Pulsed ex vivo with Recombinant Chlamydial Protease-Like Activity Factor Induces Protective Immunity Against Genital Chlamydia muridarum Challenge

We have shown that immunization with soluble recombinant (r) chlamydial protease-like activity factor (rCPAF) and a T helper (Th) 1 type adjuvant can induce significantly enhanced bacterial clearance and protection against Chlamydia–induced pathological sequelae in the genital tract. In this study,...

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Bibliographic Details
Main Authors: Bernard eArulanandam, Weidang eLi, Ashlesh eMurthy, Bharatkumar eChaganty, M N Guentzel, janakiram eseshu, James Patrick Chambers, Guangming eZhong
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-12-01
Series:Frontiers in Immunology
Subjects:
Chlamydia trachomatis
Vaccination
CPAF
Denditic Cells
Genital Pathology
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2011.00073/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2011.00073/full

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