Autophagy-related IRGM polymorphism is associated with mortality of patients with severe sepsis.

<h4>Objective</h4>Autophagy is the regulated catabolic process for recycling damaged or unnecessary organelles, which plays crucial roles in cell survival during nutrient deficiency, and innate immune defense against pathogenic microorganisms. Autophagy has been also reported to be invol...

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Bibliographic Details
Main Authors: Tomonori Kimura, Eizo Watanabe, Teruo Sakamoto, Osamu Takasu, Toshiaki Ikeda, Kazumi Ikeda, Joji Kotani, Nobuya Kitamura, Tomohito Sadahiro, Yoshihisa Tateishi, Koichiro Shinozaki, Shigeto Oda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24626347/?tool=EBI