Enhanced antitumor efficacy of a vascular disrupting agent combined with an antiangiogenic in a rat liver tumor model evaluated by multiparametric MRI.

Enhanced antitumor efficacy of a vascular disrupting agent combined with an antiangiogenic in a rat liver tumor model evaluated by multiparametric MRI.

A key problem in solid tumor therapy is tumor regrowth from a residual viable rim after treatment with a vascular disrupting agent (VDA). As a potential solution, we studied a combined treatment of a VDA and antiangiogenic. This study was approved by the institutional ethical committee for the use a...

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Bibliographic Details
Main Authors: Feng Chen, Yingmei Feng, Kaier Zheng, Frederik De Keyzer, Junjie Li, Yuanbo Feng, Marlein Miranda Cona, Huaijun Wang, Yansheng Jiang, Jie Yu, Guy Marchal, Catherine Verfaillie, Bart De Geest, Raymond Oyen, Yicheng Ni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3399789?pdf=render

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http://europepmc.org/articles/PMC3399789?pdf=render

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