Nitrosative/oxidative stress conditions regulate thioredoxin-interacting protein (TXNIP) expression and thioredoxin-1 (TRX-1) nuclear localization.

Thioredoxin (TRX-1) is a multifunctional protein that controls the redox status of other proteins. TRX-1 can be found in the extracellular milieu, cytoplasm and nucleus, and it has distinct functions in each environment. Previously, we studied the intracellular localization of TRX-1 and its relation...

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Bibliographic Details
Main Authors: Fernando Toshio Ogata, Wagner Luiz Batista, Adriano Sartori, Tarsis Ferreira Gesteira, Hiroshi Masutani, Roberto Jun Arai, Junji Yodoi, Arnold Stern, Hugo Pequeno Monteiro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3869934?pdf=render