Pharmacological and Toxicological Threshold of Bisammonium Tetrakis 4-(N,N-Dimethylamino)pyridinium Decavanadate in a Rat Model of Metabolic Syndrome and Insulin Resistance

Vanadium(IV/V) compounds have been studied as possible metallopharmaceutical drugs against diabetes mellitus. However, mechanisms of action and toxicological threshold have been tackled poorly so far. In this paper, our purposes were to evaluate the metabolic activity on dyslipidemia and dysglycemia...

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Main Authors: Samuel Treviño, Alfonso Díaz, Eduardo Sánchez-Lara, Víctor Enrique Sarmiento-Ortega, José Ángel Flores-Hernández, Eduardo Brambila, Francisco J. Meléndez, Enrique González-Vergara
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Bioinorganic Chemistry and Applications
Online Access:http://dx.doi.org/10.1155/2018/2151079