Mechanisms of stimulation of SAGA-mediated nucleosome acetylation by a transcriptional activator

Eukaryotic gene expression requires the coordination of multiple factors to overcome the repressive nature of chromatin. However, the mechanistic details of this coordination are not well understood. The SAGA family of transcriptional coactivators interacts with DNA-binding activators to establish r...

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Bibliographic Details
Main Authors: Sannie J. Culbertson, Michael A. Shogren-Knaak
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Biochemistry and Biophysics Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580820301941