BMP4 Enhances Foam Cell Formation by BMPR-2/Smad1/5/8 Signaling

Atherosclerosis and its complications are characterized by lipid-laden foam cell formation. Recently, an obvious up-regulation of BMP4 was observed in atherosclerotic plaque, however, its function and the underlying mechanism remains unknown. In our study, BMP4 pretreatment induced macrophage foam c...

Full description

Bibliographic Details
Main Authors: Jun Feng, Jiangfei Gao, Yuxin Li, Yanhua Yang, Lili Dang, Yuanpeng Ye, Jingyuan Deng, Antai Li
Format: Article
Language:English
Published: MDPI AG 2014-03-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/15/4/5536